California Cancer Reporting System Standards, Volume III

IF1135: Primary Site, AJCC N - Ed 7, ICDO3

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SEER

EDIT SETS

California Hospital Transmit

Eureka Admission Level

FIELDS

Date of Diagnosis [NAACCR #390]

TNM Edition Number [NAACCR #1060]

Primary Site [NAACCR #400]

Histologic Type ICD-O-3 [NAACCR #522]

Behavior Code ICD-O-3 [NAACCR #523]

Age at Diagnosis [NAACCR #230]

CS Site-Specific Factor 10 [NAACCR #2864]

CS Site-Specific Factor 25 [NAACCR #2879]

Grade [NAACCR #440]

TNM Clin N [NAACCR #950]

TNM Path N [NAACCR #890]

Sex [NAACCR #220]

TABLE

AJC7NC.DBF

AJC7NP.DBF

AJC7SIGP.DBF

MESSAGE

IF1135: AJCC N code problem
IF1135: AJCC Path N code is invalid for site/hist combination
IF1135: AJCC Clin N code is invalid for site/hist combination
IF1135: AJCC Clin N code should = 88 for site/hist combination
IF1135: AJCC Path N code should = 88 for site/hist combination

specification

This edit is skipped if any of the following conditions are true:

Year of Date of Diagnosis is less than 2015 or empty (unknown)
TNM Edition Number is not = 07 and not = 88
TNM Clin N and TNM Path N are both empty
Histologic Type ICD-O-3 is blank
Behavior Code ICD-O-3 = 0 (benign) or 1 (borderline)

TNM Clin N and TNM Path N may be blank. If entered, they will be edited site-specifically.

The site-specific TNM N values are listed below. The number next to each site group indicates the chapter in the AJCC Cancer Staging Manual, Edition 7. The sites for each chapter are listed along with the histologies requiring AJCC staging. The allowable values for the clinical and pathologic N codes are listed under TNM N. When there is a difference in allowable values for clinical and pathologic N codes, they will be specified separately.

3. Lip and Oral Cavity

Sites:

C000-C006,C008,C009

C020-C023,C028,C029

C030,C031,C039

C040,C041,C048,C049

C050,C058,C059

C060-C062,C068,C069

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,2A,2B,2C,3

4. Pharynx

4A. Oropharynx and Hypopharynx

Sites:

C019, C024

C051-C052

C090-C091, C098-C099

C100, C102-C104, C108-C109

C129

C130-C132, C138-C139

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,2A,2B,2C,3

4B. Nasopharynx

Sites:

C110, C112-C113, C118-C119

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3,3A,3B

4C. Nasopharynx

Sites:

C111

Discriminator (CS Site-Specific Factor25):

010

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3,3A,3B

4D. Oropharynx

Sites:

C111

Discriminator (CS Site-Specific Factor25):

020

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,2A,2B,2C,3

5. Larynx

5A. Supraglottis, Subglottis, Other

Sites:

C101, C321-C322

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,2A,2B,2C,3

5B. Glottis

Sites:

C320, C328-C329

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980, 8981

TNM N:

X,0,1,2,2A,2B,2C,3

6. Nasal Cavity and Paranasal Sinuses

Sites:

C300, C310-C311

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,2A,2B,2C,3

7. Major Salivary Glands

Sites:

C079

C080,C081,C088,C089

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8982

TNM N:

X,0,1,2,2A,2B,2C,3

8. Thyroid Gland

8A. Thyroid: Papillary/follicular, age less than 045

Sites:

C739

Histologies Requiring AJCC Staging:

8000-8015, 8022, 8033-8344, 8350-8420, 8440-8508,

8514-8576, 8940-8950, 8980-8981

Age at Diagnosis:

less than 045

Grade:

1-3 or 9

TNM N:

X,0,1,1A,1B

8B. Thyroid: Papillary/follicular, age greater than or equal 045 but not 999

Sites:

C739

Histologies Requiring AJCC Staging:

8000-8015, 8022, 8033-8344, 8350-8420, 8440-8508,

8514-8576, 8940-8950, 8980-8981

Age at Diagnosis:

greater than or equal to 045, but not equal 999

Grade:

1-3 or 9

TNM N:

X,0,1,1A,1B

8C. Thyroid: Papillary/follicular, age equal 999 (unknown)

Sites:

C739

Histologies Requiring AJCC Staging:

8000-8015, 8022, 8033-8344, 8350-8420, 8440-8508,

8514-8576, 8940-8950, 8980-8981

Age at Diagnosis:

equal 999

Grade:

1-3 or 9

TNM N:

X,0,1,1A,1B

8D. Thyroid: Medullary

Sites:

C739

Histologies Requiring AJCC Staging:

8345-8347, 8430, 8510, 8512-8513

Grade:

1-3 or 9

TNM N:

X,0,1,1A,1B

8E. Thyroid: Anaplastic

Sites:

C739

Histologies Requiring AJCC Staging:

8020-8021, 8030-8032

TNM N:

X,0,1,1A,1B

8F. Thyroid: Anaplastic

Sites:

C739

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

Grade:

TNM N:

X,0,1,1A,1B

9. Mucosal Melanoma of the Head and Neck

Sites:

C000-C006, C008-C009

C019

C020-C024, C028-C029

C030-C031, C039

C040-C041, C048-C049

C050-C052, C058-C059

C060-C062, C068-C069

C090-C091, C098-C099

C100-C104, C108-C109

C110-C113, C118-C119

C129

C132, C138-C139

C140, C142, C148

C300

C310-C311

C320-C323, C328-C329

Histologies Requiring AJCC Staging:

8720-8790

TNM N:

X,0,1

10. Esophagus and Esophagus Gastric Junction

10A. Esophagus

Sites:

C150-C155, C158-C159

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3

10B. Esophagus Gastric Junction

Sites:

C160-C162

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8247-8248, 8250-8576, 8940-8950, 8980-8981

Discriminator (CS Site-Specific Factor25):

020, 040, 060 (for C161-C162), 982 (982 is for C160 only)

TNM N:

X,0,1,2,3

11. Stomach

Sites:

C161-C162 and Discriminator (CS Site-Specific Factor 25) = 000, 030, 100, 999

C163-C166, C168-C169 and Discriminator (CS Site-Specific Factor 25) = 981

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8247-8248, 8250-8576, 8940-8950, 8980-8990

TNM N:

X,0,1,2,3.3A,3B

12. Small Intestine

Sites:

C170-C172, C178-C179

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8247-8248, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2

13. Appendix

13A. Appendix: Carcinoma

Sites:

C181

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8247-8248, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3

13B. Appendix: Carcinoid

Sites:

C181

Histologies Requiring AJCC Staging:

8240-8242, 8246, 8249, 8153

TNM N:

X,0,1

14. Colon and Rectum

Sites:

C180, C182-C189

C199

C209

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8247-8248, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,1A,1B,1C,2,2A,2B

15. Anus

Sites:

C210-C212, C218

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3

16. Gastrointestinal Stromal Tumor (GIST)

16A. GIST: Gastric

Sites:

C160-C169

C480-C488 and CS Site-Specific Factor 10 = 020 (Omentum)

Histologies Requiring AJCC Staging:

8935-8936

TNM N:

X,0,1

16B. GIST: Small Intestine

Sites:

C150-C159

C170-C172, C178, C179

C180-C189

C199

C209

C480-C488 and CS Site-Specific Factor 10 not = 020 (Omentum)

Histologies Requiring AJCC Staging:

8935-8936

TNM N:

X,0,1

17. Neuroendocrine Tumors (NET)

17A. NET: Stomach

Sites:

C160-C169

Histologies Requiring AJCC Staging:

8153, 8240-8242, 8246, 8249

TNM N:

X,0,1

17B. NET: Small Intestine and Ampulla of Vater

Sites:

C170-C179

C241

Histologies Requiring AJCC Staging:

8153, 8240-8242, 8246, 8249

TNM N:

X,0,1

17C. NET: Colon and Rectum

Sites:

C180, C182-C189

C199, C209

Histologies Requiring AJCC Staging:

8153, 8240-8242, 8246, 8249

TNM N:

X,0,1

18. Liver

18A. Sites:

C220

Histologies Requiring AJCC Staging:

8170-8175

TNM N:

X,0,1

18B. Sites:

C221

Histologies Requiring AJCC Staging:

8170-8175

TNM N:

X,0,1,88

19. Intrahepatic Bile Ducts

19A. Sites:

C220

Histologies Requiring AJCC Staging:

8160, 8161, 8180

TNM N:

X,0,1, 88

19B. Sites:

C221

Histologies Requiring AJCC Staging:

8160, 8161, 8180

TNM N:

X,0,1

20. Gallbladder

Sites:

C239

C240 and Discriminator (CS Site-Specific Factor 25) = 030

Histologies Requiring AJCC Staging:

8000-8152,8154-8231, 8243-8245, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2

21. Perihilar Bile Ducts

Sites:

C240 and Discriminator (CS Site-Specific Factor 25) = 010, 020, 050,

060, 999

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2

22. Distal Bile Duct

Sites:

C240 and Discriminator (CS Site-Specific Factor 25) = 040, 070

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

23. Ampulla of Vater

Sites:

C241

Histologies Requiring AJCC Staging:

8000-8152, 8154-8231, 8243-8245, 8250-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

24. Exocrine and Endocrine Pancreas

Sites:

C250-C254, C257-C259

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8971, 8980-8981

TNM N:

X,0,1

25. Lung

Sites:

C340-C343,C348,C349

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3

26. Pleural Mesothelioma

Sites:

C384

Histologies Requiring AJCC Staging:

9050-9053

TNM N:

X,0,1,2,3

27. Bone

Sites:

C400-C403, C408-C409

C410-C414, C418-C419

Histologies Permitting AJCC Staging:

8800-9136, 9142-9582

TNM N:

X,0,1

28. Soft Tissue Sarcoma

Peritoneum - not female

Sites:

C481-C482, C488

Histologies:

8800-8820, 8823-8934, 8940-9136, 9142-9582

CS Site-Specific Factor25 = not 002 (that is, not female)

Peritoneum - female

Sites:

C481-C482, C488

Histologies:

8800-8820, 8823-8921, 9120-9136, 9142-9582

CS Site-Specific Factor25 = 002 (female)

Heart,Mediastinum, Soft Tissue

Sites:

C380-C383, C388

C470-C476, C478-C479

C490-C496, C498-C499

Histologies:

8800-8820, 8823-8935, 8940-9136, 9142-9582

Retroperitoneum

Sites:

C480

Histologies:

8800-8820, 8823-8934, 8940-9136, 9142-9582

TNM N:

X,0,1

29. Cutaneous Squamous Cell Carcinoma and other Cutaneous Carcinomas

Sites:

C440, C442-C449, C632

Histologies Requiring AJCC Staging:

8000-8246, 8248-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,2A,2B,2C,3

30. Merkel Cell Carcinoma

Sites:

C440, C442-C449,

C510-C512, C518-C519

C600-C602, C608-C609

C632

Histologies Requiring AJCC Staging:

8247

TNM N:

X,0,1,1A,1B,2

31. Melanoma of the Skin

Sites:

C440-C449

C510-C512,C518,C519

C600-C602, C608, C609

C632

Histologies Requiring AJCC Staging:

8720-87900

TNM N:

X,0,1,1A,1B,2,2A,2B,2C,3

32. Breast

Sites:

C500-C506,C508,C509

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981, 9020

TNM N:

Clin: X,0,1,2,2A,2B,3,3A,3B,3C

Path: X,0,0I-,0I+,0M-,0M+,1,1A,1B,1C,1MI,2,2A,2B,3,3A,3B,3C

33. Vulva

Sites:

C510-C512,C518,C519

Histologies Requiring AJCC Staging:

8000-8246, 8248-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,1A,1B,2,2A,2B,2C,3

34. Vagina

Sites:

C529

Histologies Requiring AJCC Staging:

8000-8576, 8800-8801, 8940-8950, 8980-8981

TNM N:

X,0,1

35. Cervix Uteri

Sites:

C530,C531,C538,C539

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

36. Corpus Uteri

36A. Corpus Uteri: Carcinomas

Sites

C540-C543, C548-C549

C559

Histologies Requiring AJCC Staging:

8000-8790, 8950-8951, 8980-8981

TNM N:

X,0,1,2

36B. Corpus Uteri: Leiomyosarcoma and Endometrial Stromal Sarcoma

Sites:

C540-C543, C548-C549

C559

Histologies Requiring AJCC Staging:

8800, 8890-8898, 8900-8921, 8930-8931, 8935

TNM N:

X,0,1

36C. Corpus Uteri: Adenosarcoma

Sites:

C540-C543, C548-C549

C559

Histologies Requiring AJCC Staging:

8933

TNM N:

X,0,1

37. Ovary and Peritoneal Carcinomas

37A. Ovary

Sites:

C569

Histologies Requiring AJCC Staging:

8000-8576, 8590-8671, 8930-9110

TNM N:

X,0,1

37B. Peritoneal Carcinomas

Sites:

C481-C482, C488 (Sex = 2,female) and Discriminator (CS Site-Specific Factor 25) = 002

Histologies Requiring AJCC Staging:

8000-8576, 8590-8671, 8930-8934, 8940-9110

TNM N:

X,0,1

38. Fallopian Tube

Sites:

C570

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

39. Gestational Trophoblastic Tumors

Sites:

C589

Histologies Requiring AJCC Staging:

9100-9105

TNM N:

40. Penis

Sites:

C600-C602,C608,C609

Histologies Requiring AJCC Staging:

8000-8246, 8248-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3

41. Prostate

Sites:

C619

Histologies Requiring AJCC Staging:

8000-8110, 8140-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

42. Testis

Sites:

C620,C621,C629

Histologies Requiring AJCC Staging:

8000-8576, 8590-8670, 8940-8950, 8980-8981, 9060-9090, 9100-9105

TNM N:

X,0,1,2,3

43. Kidney

Sites:

C649

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

44. Renal Pelvis and Ureter

Sites:

C659

C669

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3

45. Urinary Bladder

Sites:

C670-C679

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2,3

46. Urethra

Sites:

C680

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1,2

47. Adrenal

47A. Adrenal Cortex

Sites:

C740

Histologies Requiring AJCC Staging:

8010, 8140, 8370

TNM N:

X,0,1

47B. Adrenal Cortical Carcinoma

Sites:

C749

Histologies Requiring AJCC Staging:

8370

TNM N:

X,0,1

48. Carcinoma of the Eyelid

Sites:

C441

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

49. Conjunctiva

Sites:

C690

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

50. Malignant Melanoma of the Conjunctiva

Sites:

C690

Histologies Requiring AJCC Staging:

8720-8790

TNM N:

Clin: X,0,0A,0B,1

Path: X,0,1

51. Malignant Melanoma of Uvea

51A. Ciliary Body and Choroid

Sites:

C693

C694 (CS Site-Specific Factor 25 = 010 or 999)

Histologies Requiring AJCC Staging:

8720-8790

TNM N:

X,0,1

51B. Iris

Sites:

C694 (CS Site-Specific Factor 25 = 020)

Histologies Requiring AJCC Staging:

8720-8790

TNM N:

Clin: X,0,1

Path: X,0,1,1A,1B,1C

52. Retinoblastoma

Sites:

C692

Histologies Requiring AJCC Staging:

9510-9514

TNM N:

X,0,1,2

53. Carcinoma of the Lacrimal Gland

Sites:

C695 and CS Site-Specific Factor25 = 015

Histologies Requiring AJCC Staging:

8000-8576, 8940-8950, 8980-8981

TNM N:

X,0,1

54. Sarcoma of the Orbit

Sites:

C696, C698

Histologies Requiring AJCC Staging:

8800-8936, 8940-9136, 9141-9508, 9520-9582

TNM N:

X,0,1

55. Ocular Adnexal Lymphoma

Sites:

C441, C690, C695-C696

Histologies Requiring AJCC Staging:

9590-9699, 9702-9738, 9811-9818, 9820-9837

TNM N:

X,0,1,2,3,4

56. Brain and Spinal Cord

Sites:

C700, C701, C709, C710-C719, C720-C729, C751-C753

Histologies Requiring AJCC Staging:

8000, 8680-9136,9141-9582

TNM N:

57. Lymphoid Neoplasms

57A. Hodgkin and Non-Hodgkin

Sites:

C000-C419, C422-C423, C425-C440, C442-C689, C691-C694, C698-C809

Histologies Requiring AJCC Staging:

9590-9699, 9702-9729, 9735, 9737-9738, 9811-9818, 9823, 9827, 9837

TNM N:

57B. Primary Cutaneous Lymphomas

Sites:

C440-C449

C510-C512, C518-C519

C600-C602, C608-C609, C632

Histologies Requiring AJCC Staging:

9700,9701

TNM N:

X,0,1,1A,1B,2,2A,2B,3

All Others

TNM N:

historical changes

In the SEER*Edits software, the title of this edit is: IF507
03/2015	Per NAACCR v15, new edit added.