IF1223: TNM Path Stage Group and TNM Clin Stage Group must = same in situ stage
IF1223: For TNM Path T [value], TNM Path M [value] must be coded as negative for involvement
IF1223: TNM Path T and TNM Clin T must = same in situ T category
IF1223: For TNM Path T [value], TNM Path Stage Group [value] must be coded in situ stage group
IF1223: For TNM Path T [value], TNM Path [value] must be coded as negative for involvement

specification

The purpose of this edit is to verify that TNM Path N, TNM Path M, TNM Path Stage Group, TNM Clin T, and TNM Clin Stage Group are coded consistently for cases where TNM Path T indicates an in situ tumor(TNM Path T = pIS, pA, pISU, pISD, or pA).

This edit enforces the statement in the AJCC manual on page 12: “Carcinoma in situ (CIS) is an exception to the stage grouping guidelines. By definition, CIS has not involved any structure in the primary organ that would allow tumor cells to spread to regional nodes or distant sites. Therefore, pTis cN0 cM0 should be reported as both clinical and pathologic stage 0.” The statement on page 499 for bladder takes precedence for this site: “Pathologic staging is based on the histologic review of the radical or partial cystectomy specimen.” Where pTis is an incidental finding at surgery, TNM Clin T is allowed to be blank and TNM Stage Group is allowed to = 99. The edit TNM Clin T,N,M, In Situ (COC) checks that TNM Clin N, TNM Clin M, and TNM Clin Stage Group are coded consistently with TNM Clin T for in situ tumors.

This edit is skipped if any of the following conditions are true:

Year of Date of Diagnosis is less than 2016, blank (unknown), or invalid
Type of Reporting Source = 7
Behavior Code ICD-O-3 = 0 (benign) or 1 (borderline)
TNM Path T is not = pIS, pA, pISU, pISD, or pA
TNM Edition Number not = 07, U7
TNM Path Descriptor = 4 or 6

If TNM Path T = pIS, pA, pISU, or pISD:

If TNM site/histology group = Bladder:

TNM Path N must = p0 (negative nodes pathologically), pX (nodes not pathologically evaluated),c0 (clinically negative nodes) or blank (criteria not met for pathologic staging of bladder)
TNM Path M must = c0 (no clinically positive metastasis) or blank (criteria not met for pathologic staging of bladder)
TNM Path Stage Group must = 0IS or 0A (codes indicating in situ/noninvasive based on pathologic evaluation of T and N) or 99 (criteria not met for pathologic staging of bladder).
TNM Clin T must = TNM Path T or blank (incidental finding of an in situ at surgery)
TNM Clin Stage Group must = TNM Path Stage Group if both are coded and TNM Path Stage Group not = 99 and TNM Clin Stage Group not = 99. (Other edits check that TNM Path Stage Group and TNM Clin Stage Group are not blank.)

For all other AJCC groups:

TNM Path N must = p0, p0I-, p0I+, p0M-, p0M+ (negative nodes pathologically), pX (nodes not pathologically evaluated), c0 (clinically negative nodes).
TNM Path M must = c0, c0I+ (no clinically positive metastasis)
TNM Path Stage Group must = 0, 0A, or 0IS (codes indicating pathologic stage group based on AJCC instructions for pTis) or 99
TNM Clin T must = TNM Path T or blank (incidental finding of in situ at surgery)
TNM Clin Stage Group must = TNM Path Stage Group if both are coded and TNM Path Stage Group not = 99 and TNM Clin Stage Group not = 99. (Other edits check that TNM Path Stage Group and TNM Clin Stage Group are not blank.)

Only TNM Path N and TNM Path M are edited for the following TNM groups. In situ carcinomas are recognized by AJCC, but there is no stage grouping.

Carcinoma of Conjunctiva
Malignant Melanoma of Conjunctiva

This edit is skipped for the following TNM groups (AJCC does not recognize or does not stage in situ tumors for these sites, though in situ may be assigned by a pathologist):

7. Major Salivary Glands

8. Thyroid Gland (08A-08F)

9. Mucosal Melanoma Head and Neck

13B. Appendix, Carcinoid

16. GIST

17. NET Small Intestine and Ampulla of Vater, NET Colon and Rectum (17B, 17C)

18. Liver

36B. Corpus Sarcoma

36C. Corpus Adenosarcoma

37A. Ovary

39. Gestational Trophoblastic Tumors

41. Prostate

43. Kidney

47. Adrenal (47A, 47B)

51A. Melanoma of Choroid

51B. Melanoma of Iris

53. Carcinoma of the Lacrimal Gland

54. Sarcoma of the Orbit

57B. Primary Cutaneous Lymphoma

historical changes

In the SEER*Edits software, the title of this edit is: IF605.
08/2016	Per NAACCR v16, new edit added.
09/2016	Per NAACCR v16A: Corrected logic for first INLIST of primary sites for site/histology group 57A, 000-419-440 changed to 000-440. Description and logic updated to skip edit for Carcinoma of Conjunctiva, Melanoma of Conjunctiva. Corrected Edit Logic to include 9727 as lymphoma rather than lymphoma/leukemia code, to delete 9728-9729 as obsolete codes. Added Group 57C, C420, C421, C424, 9811-9818, 9837,to Edit Logic
11/2016	Per NAACCR v16B: Name changed from TNM T,N,M, In Situ (CoC) to TNM Path T,N,M, In Situ (COC). Description and Edit Logic updated to allow TNM Clin T to be blank and TNM Clin Stage Group to equal 99 when TNM Path T is in situ. This logic assumes that In situ carcinoma was not diagnosed clinically and is an incidental finding at surgery. Logic statements requiring that TNM Clin N, TNM Clin M, and TNM Clin Stage Group are also coded consistently with TNM Path T = in situ removed from edit; consistency of coding for TNM Clin fields checked in another edit, TNM Clin T,N,M, In Situ (COC). Description and logic updated to edit Carcinoma of Conjunctiva and Melanoma of Conjunctiva for TNM Path N and TNM Path M and only skip for TNM Path Stage Group. Error messages updated to be more specific about coding problems Corrected edit logic for assigning site/histology group 011 to group 10B or 999 based on histology and CS Site-Specific Factor 25.
03/2017	Per NAACCR v16D: Description, logic modified to skip if TNM Edition Number not = 07,U7. Description, edit logic modified to omit comparison between clin TNM and stage group and path TNM and stage group values. Modified logic, format of character string, e.g. "pxxb", 2,3. Logic corrected to skip for group 009, Mucosal Melanoma of Head and Neck. Description, logic modified to not include pNX as allowable code for in situ carcinomas. Corrected MATCH patterns (they were not precise enough for EDITS50.